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    Omega 3 Fish Oil May Boost Disease Fighting Protein at the Genetic Level

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    Omega 3 Essential Fatty Acids may stimulate a protein to suppress over expression of disease and cancer associated genes according to a study by researchers at the University of Wisconsin.

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    Omega 3 Essential Fatty Acids have been studied since the 1970’s but there is still only strong correlation between health benefits and omega 3 – researchers have not identified the specific processes that take place. A recent study led by Professor John Denu of the University of Wisconsin School of Medicine may have found a link at the genetic level.

    Denu and his team of researchers observed that long chain fatty acids – like omega 3 – bind to a repressor protein called SIRT-6 making it 35 times more active in repressing its target genes.

    Israeli researchers had previously reported that more active expressions of this protein had caused mice to live longer and researchers at Harvard University had observed that animals lacking SIRT-6 had defects in metabolism, genomic instability and spontaneously formed cancers.

    SIRT-6 acts as a suppressor to gene expression for genes involved in the promotion of inflammatory metabolic-based and age related diseases. Gene expression refers to the process of transferring DNA information used by our genes to determine the structure and function of individual cells.

    This recent research indicates the health affects of omega 3 might be through a stimulated pathway at the genetic level involving SIRT-6.

    Fish oil has long been thought to provide health benefits because it delivers omega 3 essential fatty acids and two in particular – eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) which the body needs for cellular health. The human body does not produce these substances so they need to be ingested through diet.

    Western diets are generally high in omega-6 and low in omega-3 essential fatty acids, specifically EPA and DHA and omega 3 supplements have grown in popularity.

    “Researchers have long understood that there are real benefits associated with healthy levels of omega 3” said Tess Mckay, a customer service representative for Ballena Nelle, a health supplement company. “But this research could be extremely significant because it is the first to go beyond a correlation of omega 3 levels and health improvement. This research explains a process.”

    The Food and Drug Administration has stated that omega-3 fish oils may reduce the risk of heart disease but this research indicates there is still much to learn about how they work.

    Ballena Nelle is a health supplement company that manufactures a pharmaceutical grade omega 3 fish oil. It uses sardines and anchovies from the southern Pacific, because they have the highest concentration of DHA and EPA and the lowest exposure to contaminants. “These two species are the cleanest and highest quality source of raw fish oil in the world,” said Mckay.

    The fish oil is then purified, third party tested to ensure zero contaminants and manufactured into soft gel tablets in a U.S. manufacturing facility.

    Ballena Nelle Pharmaceutical Grade Omega-3 Fish Oil contains 55% EPA and DHA per capsule. Other fish oil supplements often contain less than 20% EPA and DHA and are composed mostly of fillers.

    Ballena Nelle products are based on clinical research and recommendations from a naturopathic advisory board. All ingredients meet or exceed Good Manufacturing Practice (GMP) standards. For more information, please visit www.ballenanelle.com

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